Washington DC - President Joe Biden ended his Covid-19 isolation after testing negative twice, the White House said.

Biden said on Wednesday he was "feeling great," just under a week after he was diagnosed with Covid. He went into isolation last Thursday and was given a course of Paxlovid, a coronavirus treatment medication.

White House physician Kevin O'Connor said in a letter that the 79-year-old president tested negative on Tuesday night and again on Wednesday morning.

"His symptoms have been steadily improving, and are almost completely resolved," O’Connor wrote.

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"My symptoms were mild, my recovery was quick and I'm feeling great," Biden said a short time later from the White House Rose Garden, during a speech in which he encouraged Americans to get their booster shots as the spread of the BA.5 subvariant of Omicron continues.

He also took a jab at ex-President Donald Trump, saying: "When my predecessor got Covid, he had to get helicoptered to Walter Reed Medical Center... When I got Covid, I worked from upstairs [in the White House]."

The president called on people to get boosted and tested as needed, and turn to Paxlovid if they become ill.

"God bless you all, and now I get to go back to the Oval Office," he told the assembled media at the end of his remarks.