Kansas City, Missouri - Multiple people were injured and at least one killed after gunfire erupted at the Kansas City Chiefs Super Bowl victory rally on Wednesday, local police said.

A shooting incident at a packed parade Wednesday to celebrate the Kansas City Chiefs' Super Bowl victory killed one person and injured nine others, the city fire department said.

Of the injured, three were listed in critical condition, five serious and one non-life-threatening, a spokesman for the department told AFP. ABC News reported at least eight more victims were hospitalized with injuries not sustained from gunshots.

Kansas City police said two armed individuals were taken into custody following the shooting at Union Station, just yards from where Chiefs players had addressed cheering supporters moments earlier.

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"Anyone nearby needs to leave the area as quickly as possible to facilitate treatment of the shooting victims," local police said on X, formerly Twitter.

Fans scrambled to flee the scene as police worked to clear Union Station in an ugly end to what had been a joyous parade.

TAG24 shared footage captured on the ground moments before shots rang out. Earlier, hundreds of thousands of red-clad fans had greeted Chiefs quarterback Patrick Mahomes and his teammates as they made their way along a two-mile route on a procession of double-decker buses enveloped by a blizzard of red and gold confetti.

The Super Bowl MVP, at one stage clutching a can of beer and the Vince Lombardi Trophy, and several Chiefs players dismounted the buses, high-fived, and took selfies with fans, many of whom began lining up before dawn to snaffle prime viewing positions.

"Praying for Kansas City," Mahomes wrote on X after the shooting.

Local media had cited local officials as saying more than one million people were expected for the parade, which was held in unseasonably sunny, warm conditions in downtown Kansas City.

The Chiefs were celebrating their third Super Bowl title in five seasons after beating the San Francisco 49ers in overtime in Las Vegas on Sunday to cement the team's dynasty status.

More updated to follow.

Updated numbers total 22 people shot in the mass shooting, with one dead, according to Kansas City Police Chief Stacey Graves.

Police are still working on the total number of those injured, but at least 29 people are being treated at local hospitals. One location reported at least 11 were children, nine with gunshot wounds.

Police said three people have now been taken into custody, but their identities have not been released and their motive is under investigation.

Kansas City fire department chief Ross Grundyson said many victims have "life-threatening injuries."

President Joe Biden issued a statement, saying, "Today's events should move us, shock us, shame us into acting," Biden said in a White House statement. "What are we waiting for? What else do we need to see? How many more families need to be torn apart?"

He called on the country to "make your voice heard in Congress so we finally act to ban assault weapons, to limit high-capacity magazines, strengthen background checks, keep guns out of the hands of those who have no business owning them or handling them."

Vice President Kamala Harris also called on Congress members to pass “reasonable gun safety laws” after Wednesday’s shooting.

The victim killed at Wednesday's shooting has been identified as Kansas City-area radio DJ Lisa Lopez-Galvan.

This senseless act has taken a beautiful person from her family and this KC Community," station KKFI 90.1 FM wrote in a Facebook post.

More victims have yet to be identified.